What It Is
KI-EX-01 is a biotechnology serum designed to support skin repair, resilience, and structural integrity.
The formula delivers plant-derived extracellular vesicles (exosomes) cultured from cloned pomegranate plant cells. These vesicles carry regulatory molecules capable of influencing cellular signalling and improving communication between skin cells.
Within the SKNtelligence system this product sits in the Knowledge Index layer, delivering advanced biological intervention focused on long-term structural resilience and skin repair signalling.
Why It Matters
Ageing and environmental stress disrupt cellular communication networks in the skin.
This disruption contributes to:
• impaired repair processes
• collagen breakdown
• reduced dermal signalling
• increased cellular stress
• visible loss of firmness and resilience
Exosomes function as intercellular communication vehicles, transferring signalling molecules that help regulate cellular stress responses and structural maintenance pathways.
By improving cellular communication, KI-EX-01 helps skin maintain resilience and recover more effectively from environmental and biological stress.
The Science
KI-EX-01 is built around plant-derived exosome technology.
Extracellular Vesicle Signalling
Plant-derived vesicles carry regulatory molecules including proteins, lipids, and RNA fragments that influence cellular signalling pathways.
SUMOylation Activation
Exosome signalling can activate SUMO-1 and SUMO-2 pathways, which regulate cellular stress responses, DNA repair pathways, and protein regulation mechanisms.
Dermal Matrix Support
Exosome signalling also supports extracellular matrix communication, helping regulate collagen signalling and glycosaminoglycan production.
Together these mechanisms support improved structural resilience and adaptive cellular repair processes in the skin.
Visible Benefits
Regular use may support:
• reduction in visible wrinkles
• improved skin firmness
• improved structural resilience
• improved recovery from environmental stress
• improved hydration retention
• smoother skin texture
Over time the skin appears stronger, smoother, and more resilient.
How To Use
KI-EX-01 can be used morning or evening.
Within the SKNtelligence system it is applied after Signal Matrix products and before moisturisers or lipid products.
Routine order:
Cleanse → Signal Matrix → KI-EX-01 → Nourishment Substrate
Recommended dose:
1–2 drops applied evenly across the face.
Protocol Integration
KI-EX-01 appears in several SKNtelligence protocols.
The Regeneration Protocol
AM
SM-01 Cellular Activator
KI-Cu-01 Regeneration Amplifier
NS-01 Stabilising Substrate
PM
SM-02 Signal Amplification
KI-EX-01 Epigenetic Repair
NS-02 Ceramide Lipid
The Urban Defence Protocol
AM
SM-01 Cellular Activator
KI-Cu-03 Urban Stress Shield
NS-01 Stabilising Substrate
PM
SM-02 Signal Amplification
KI-EX-01 Epigenetic Repair
NS-02 Ceramide Lipid
The Recovery Protocol
AM
SM-01 Cellular Activator
KI-Cu-01 Regeneration Amplifier
NS-01 Stabilising Substrate
PM
SM-02 Signal Amplification
KI-EX-01 Epigenetic Repair
NS-02 Ceramide Lipid
The Longevity Protocol
AM
SM-01
KI-EX-01
NS-01
PM
SM-02
KI-Cu-01
NS-02
Ingredient List
INCI:
Aqua, Glycerin, Punica Granatum Extract, Hydroxyethyl Cellulose, Phenoxyethanol, Ethylhexylglycerin
Documentation
Download the full SKNtelligence documentation set:
• Consumer Product Brochure
• Technical Ingredient Dossier
• Professional Protocol Guide
